Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072312 | 0.83 | ALDH1A1 (0.40) | PLGKDM4EALDH1A1POLBALOX15 | |
| SCHEMBL28674762 | 0.81 | ENPP2 (0.39) | PLGKDM4EALDH1A1POLBALOX15 | |
| SCHEMBL3939571 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1POLBALOX15CACNA2D1 | |
| SCHEMBL4511200 | 0.78 | TGFBR1 (0.50) | PLGPRKCZKDRKITFLT3 | |
| SCHEMBL30506029 | 0.77 | CACNA2D1 (0.35) | PLGKDM4EALDH1A1POLBFYN | |
| SCHEMBL4856952 | 0.71 | PLAU (0.46) | KDM4EALDH1A1POLBALOX15CACNA2D1 | |
| SCHEMBL28683978 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1POLBALOX15CACNA2D1 | |
| SCHEMBL20292623 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1POLBALOX15CACNA2D1 | |
| SCHEMBL7438690 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1POLBALOX15CACNA2D1 | |
| SCHEMBL13723931 | 0.71 | CYP1A2 (0.48) | KDM4EALDH1A1POLBALOX15CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032986-A2 | NOVEL 5-(4-AMINOPHENYL)-ISOQUINOLINE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD FOR SAME, AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PROPHYLAXIS AND TREATMENT OF MEDICAL CONDITION INDUCED BY RAF KINASE HYPERACTIVITY | 주식회사 이큐스팜 (KR) | 2010-03-25 | — | — | WO | disclosed |