Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865487 | 0.83 | HPGD (0.77) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL19744072 | 0.77 | LMNA (1.00) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL70569 | 0.76 | KDM4E (0.52) | SMN1; SMN2HPGDALDH1A1POLBKMT2A | |
| SCHEMBL19476629 | 0.76 | TP53 (1.00) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL18511929 | 0.75 | HPGD (0.67) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| Water SCHEMBL3328070 | 0.74 | KDM4E (0.50) | SMN1; SMN2HPGDALDH1A1POLBKMT2A | |
| SCHEMBL11646687 | 0.74 | KDM4E (0.50) | SMN1; SMN2HPGDALDH1A1POLBKMT2A | |
| SCHEMBL2915318 | 0.73 | HDAC6 (0.74) | LMNASMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL13301500 | 0.73 | ALDH1A1 (0.63) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL5123738 | 0.73 | ALDH1A1 (0.77) | LMNASMN1; SMN2HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168947-A1 | NOVEL COMPOUND HAVING SECRETASE INHIBITORY ACTIVITY | Kiso, Yoshiaki (JP) | 2010-03-31 | — | — | EP | disclosed |