Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70569 | 0.97 | KDM4E (0.52) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL11646687 | 0.95 | KDM4E (0.50) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| Water SCHEMBL3111204 | 0.89 | KDM4E (0.42) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL742929 | 0.86 | KDM4E (0.44) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL1176813 | 0.81 | NQO1 (0.58) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL27546475 | 0.81 | KDM4E (0.44) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL12867868 | 0.77 | KMT2A (0.50) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| Chelidamic Acid SCHEMBL1535360 | 0.75 | ALOX15 (0.60) | KDM4EKMT2ADAOCSNK2A1CSNK2A2 | |
| SCHEMBL1176530 | 0.75 | ALDH1A1 (0.58) | KDM4EKMT2ACSNK2A1CSNK2A2CSNK2B | |
| Water SCHEMBL28920578 | 0.75 | TDP1 (0.58) | KDM4EKMT2AALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683793-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| US-12528983-B2 | Curable resin composition and display device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-01-20 | — | — | US | disclosed |
| US-12504564-B2 | Layered body and display device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-12-23 | — | — | US | disclosed |
| US-20250228063-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-07-10 | — | — | US | disclosed |
| US-20250215315-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250207026-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-06-26 | — | — | US | disclosed |
| CN-120077106-A | Curable composition, cured film, and display device | 住友化学株式会社 | 2025-05-30 | — | — | CN | disclosed |
| EP-4559971-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | Sumitomo Chemical Company, Limited (JP) | 2025-05-28 | — | — | EP | disclosed |
| US-20250155803-A1 | CURABLE COMPOSITION, CURED FILM, AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-05-15 | — | — | US | disclosed |
| EP-2168947-A1 | NOVEL COMPOUND HAVING SECRETASE INHIBITORY ACTIVITY | Kiso, Yoshiaki (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-5783114-A | PYRIMIDINE OR PYRIDAZINES MIXED WITH OTHER LIQUID CRYSTALLINE MATERIALS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| US-5757408-A | PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING | XEROX CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| US-5683793-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0006628-B1 | SUBSTITUTED DIHYDROPYRIDINE UREAS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1982-12-29 | — | — | EP | disclosed |
| EP-0006628-A1 | Substituted dihydropyridine ureas, process for preparing the same and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1980-01-09 | — | — | EP | disclosed |
| US-4176187-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1979-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528983-B2 | Curable resin composition and display device | TIPRL, NLRP1, RCSD1 | PTGS1 1264/4885KDM4E 1136/4885KMT2A 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.