Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460773 | 0.95 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL13460815 | 0.89 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL3410489 | 0.89 | PPARD (0.52) | PPARDPPARATAS1R3TAS1R1PPARG | |
| SCHEMBL13460937 | 0.89 | TAS1R3 (0.41) | PPARDPPARAERN1TAS1R3TAS1R1 | |
| SCHEMBL13460776 | 0.88 | PPARD (0.47) | PPARDPPARAPPARGTP53 | |
| SCHEMBL13460880 | 0.88 | ROCK2 (0.42) | PPARDPPARATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL13460820 | 0.87 | ERN1 (0.44) | PPARDPPARAERN1PPARGALDH1A1 | |
| SCHEMBL13460750 | 0.87 | PPARD (0.45) | PPARDPPARAERN1PPARGROCK2 | |
| SCHEMBL13461046 | 0.85 | PPARD (0.42) | PPARDPPARAPPARGALDH1A1HPGD | |
| SCHEMBL13460876 | 0.84 | PPARD (0.45) | PPARDPPARAERN1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |