Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454526 | 0.86 | PRMT6 (0.63) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL1347949 | 0.83 | PRMT6 (0.59) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL10245034 | 0.83 | PRMT6 (0.64) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL4640294 | 0.81 | KEAP1 (0.56) | PRMT6KEAP1KDM4E | |
| SCHEMBL28154500 | 0.80 | TAAR1 (0.61) | PRMT6TAAR1ALDH1A1TDP1KDM4E | |
| SCHEMBL14048817 | 0.80 | PRMT6 (0.60) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL12133815 | 0.79 | PRMT6 (0.59) | PRMT6KEAP1TAAR1PSMB5 | |
| SCHEMBL109478 | 0.79 | TAAR1 (0.70) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL9454365 | 0.79 | PRMT6 (0.63) | PRMT6KEAP1TAAR1ALDH1A1TDP1 | |
| SCHEMBL14141440 | 0.79 | PRMT6 (0.68) | PRMT6KEAP1TAAR1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063021-B2 | Ketolide anti-infective compounds | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-11-22 | — | — | US | disclosed |
| US-20050272672-A1 | Ketolide anti-infective compounds | KOSAN BIOSCIENCES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272672-A1 | Ketolide anti-infective compounds | HK1, AKR1D1, KHK | PRMT6 817/4885KEAP1 2319/4885TAAR1 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.