Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343091 | 0.68 | MAOA (0.38) | ALDH1A1MAOAHPGDBCHEACHE | |
| SCHEMBL8038574 | 0.60 | MAOA (0.58) | MAOABCHEACHEADRA2ASLC6A2 | |
| SCHEMBL1346213 | 0.60 | ALDH1A1 (0.36) | ALDH1A1MAOAHPGDBCHEACHE | |
| SCHEMBL13504626 | 0.60 | ALDH1A1 (0.36) | ALDH1A1MAOAHPGDBCHEACHE | |
| SCHEMBL15326871 | 0.59 | NPC1 (0.51) | ALDH1A1MAOABCHEACHEADRA2A | |
| SCHEMBL1718054 | 0.59 | MAOA (0.64) | MAOABCHEACHEADRA2ASLC6A2 | |
| SCHEMBL17073678 | 0.58 | ALDH1A1 (0.48) | ALDH1A1MAOAHPGDBCHEACHE | |
| SCHEMBL19537629 | 0.58 | ALDH1A1 (0.48) | ALDH1A1MAOAHPGDBCHEACHE | |
| SCHEMBL31316644 | 0.58 | MAOA (0.50) | ALDH1A1MAOABCHEACHEADRA2A | |
| SCHEMBL31316643 | 0.58 | MAOA (0.50) | ALDH1A1MAOABCHEACHEADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155757-B1 | NEW PROGESTERONE RECEPTOR MODULATORS | MSD OSS BV (NL) | 2012-10-31 | — | — | EP | disclosed |
| US-8063037-B2 | Progesterone receptor modulators | N. V. ORGANON (NL) | 2011-11-22 | — | — | US | disclosed |
| US-20090054400-A1 | NEW PROGESTERONE RECEPTOR MODULATORS | N.V. ORGANON | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054400-A1 | NEW PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC2, PGRMC1 | ALDH1A1 1644/4885MAOA 517/4885HPGD 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.