Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439148 | 1.00 | ACHE (0.44) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL11935403 | 1.00 | ACHE (0.44) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL17145928 | 0.83 | ACHE (0.49) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL11935278 | 0.83 | ACHE (0.49) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL17090534 | 0.79 | ALDH1A1 (0.41) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL13566017 | 0.79 | ALDH1A1 (0.41) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL11940065 | 0.73 | ACHE (0.42) | ACHEALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL13438956 | 0.73 | ACHE (0.42) | ACHEALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL13565122 | 0.73 | MEN1 (0.43) | ACHEALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL17090116 | 0.73 | ALDH1A1 (0.45) | ACHEALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | SHIONOGI & CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | NPY5R, NPY1R, NPY2R | ACHE 1699/4885ALDH1A1 3842/4885KDM4E 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.