Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144004 | 0.82 | PDE1B (0.47) | DDB1CRBNCYP19A1CYP11B1KDM1A | |
| SCHEMBL28596328 | 0.79 | GID4 (0.59) | CYP19A1CYP11B1KDM1AMAOAMAOB | |
| SCHEMBL8938889 | 0.79 | KMT2A (0.52) | DDB1CRBNKDM1AMAOAMAOB | |
| SCHEMBL13464881 | 0.72 | ALOX15 (0.50) | CYP19A1 | |
| SCHEMBL28917213 | 0.71 | GID4 (0.54) | CYP19A1CYP11B1KDM1AMAOAMAOB | |
| SCHEMBL28603159 | 0.71 | KDM1A (0.55) | CYP19A1CYP11B1KDM1AMAOAMAOB | |
| SCHEMBL5709325 | 0.71 | CA1 (0.54) | CYP19A1KDM1AMAOAMAOBGID4 | |
| SCHEMBL6306064 | 0.71 | GID4 (0.68) | KDM1AMAOAMAOBGID4SLC6A2 | |
| SCHEMBL9149066 | 0.71 | DRD2 (0.47) | DDB1CRBNCYP19A1CYP11B1DRD2 | |
| SCHEMBL12856838 | 0.70 | SLC5A2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260051-B1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | disclosed |