Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425988 | 0.77 | KMT2A (0.38) | PLK1SIGMAR1KMT2AMEN1NPC1 | |
| SCHEMBL13465631 | 0.75 | CXCR5 (0.50) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL13465633 | 0.75 | IDO1 (0.32) | ALDH1A1KDM4EIDO1ELANECXCR5 | |
| SCHEMBL12427178 | 0.75 | MEN1 (0.49) | PLK1KMT2AMEN1NPC1CYP1A2 | |
| SCHEMBL14089567 | 0.75 | ALDH1A1 (0.37) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL13466588 | 0.71 | SLC22A12 (0.43) | CYP2D6MAPTALDH1A1KDM4EGAA | |
| SCHEMBL5535163 | 0.71 | PTPN1 (0.47) | PLK1SIGMAR1KMT2AMEN1NPC1 | |
| SCHEMBL10904256 | 0.71 | PTPN22 (0.48) | SIGMAR1MAPTKDM4ETDP1 | |
| SCHEMBL8584659 | 0.69 | CYP2A6 (0.41) | PLK1SIGMAR1KMT2AMEN1NPC1 | |
| SCHEMBL2203473 | 0.67 | NPC1 (0.48) | PLK1SIGMAR1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964861-B1 | ACETYLENE-BASED POLYMER | NAT INST OF ADVANCED IND SCIEN (JP) | 2012-10-17 | — | — | EP | disclosed |