Biphenyl

Biphenyl

SCHEMBL134670

C1CCC(C2CCCCC2)CC1.CCOC(C)OCC.CN(C)C=O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ADH1A P07327 6/20 0.38
ADH1C P00326 4/20 0.38
ADH1B P00325 1/20 0.38
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7905888 0.85 LMNA (0.57) LMNA
Dimethylformamide SCHEMBL314310 0.83 LMNA (0.60) LMNATSHR
SCHEMBL3113994 0.81 LMNA (0.57) LMNA
Dimethylformamide SCHEMBL131192 0.79 LMNA (0.55) LMNATSHR
Dimethylformamide SCHEMBL133174 0.79 LMNA (0.55) LMNATSHR
SCHEMBL7024963 0.77 LMNA (0.46) LMNAADH1AADH1CADH1B
SCHEMBL10416642 0.74 LMNA (0.43) LMNAADH1AADH1CADH1BTSHR
Dimethylformamide SCHEMBL9464389 0.72 TSHR (0.47) LMNATSHR
Cyclopropane SCHEMBL1406305 0.72 LMNA (0.80) LMNA
SCHEMBL7847095 0.72 LMNA (0.80) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080308426-A1 Electrochemical Method for the Production of Betulin Aldehyde REGENTS OF THE UNIVERSITY OF MINNESOTA 2008-12-18 US claimed
WO-2006105357-A2 ELECTROCHEMICAL METHOD FOR THE PRODUCTION OF BETULIN ALDEHYDE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-10-05 WO claimed
US-10766972-B2 Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-09-08 US disclosed
US-10414841-B2 Modified conjugated diene-based polymer, method for preparing the same and rubber composition including the same LG CHEM, LTD. (KR) 2019-09-17 US disclosed
EP-3260476-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2019-05-08 EP disclosed
CN-109384981-A Modified conjugated diene rubber composition and tire 旭化成株式会社 2019-02-26 CN disclosed
CN-109384982-A Modified conjugated diene polymer composition and tire 旭化成株式会社 2019-02-26 CN disclosed
US-20180037674-A1 Modified Conjugated Diene-Based Polymer and Method for Producing the Same, and Modified Conjugated Diene-Based Polymer Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-02-08 US disclosed
US-20180016369-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING THE SAME AND RUBBER COMPOSITION INCLUDING THE SAME LG CHEM, LTD. (KR) 2018-01-18 US disclosed
EP-3260476-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2017-12-27 EP disclosed
EP-3246344-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING SAME, AND RUBBER COMPOSITION CONTAINING SAME LG Chem, Ltd. (KR) 2017-11-22 EP disclosed
EP-1293197-A1 PROCESS FOR PRODUCING PHOSPHOLIPID-CONTAINING DRUGS Takeda Chemical Industries, Ltd. (JP) 2003-03-19 EP disclosed
EP-1268486-A2 FUSED HETEROCYCLIC DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 2003-01-02 EP disclosed
WO-2001074823-A2 FUSED HETEROCYCLIC DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-10-11 WO disclosed
US-5169850-A Neurotropic or hypotensive agents AMERICAN CYANAMID COMPANY (US) 1992-12-08 US disclosed
US-5059691-A Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators AMERICAN CYANAMID COMPANY (US) 1991-10-22 US disclosed
US-4175087-A ENAMINOKETONES WITH ALKYLLITHIUM ELI LILLY AND COMPANY (US) 1979-11-20 US disclosed
US-3979410-A Intermediate α-acyl-β-dialkylamino-2-nitrostyrenes HOFFMANN-LA ROCHE INC. (US) 1976-09-07 US disclosed
US-3976639-A Intermediates for indoles HOFFMANN-LA ROCHE INC. (US) 1976-08-24 US disclosed
US-3931225-A Process for preparing o-nitrobenzylketones HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed