Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL314310 | 0.95 | LMNA (0.60) | LMNATSHRTHRB | |
| Dimethylformamide SCHEMBL131192 | 0.91 | LMNA (0.55) | LMNATSHRTHRB | |
| Butane SCHEMBL11540528 | 0.85 | LMNA (0.48) | LMNA | |
| Dimethylformamide SCHEMBL9464389 | 0.83 | TSHR (0.47) | LMNATSHRTHRB | |
| Butane SCHEMBL2557609 | 0.83 | LMNA (0.63) | LMNATHRB | |
| Butane SCHEMBL818136 | 0.83 | LMNA (0.63) | LMNATSHRTHRB | |
| Butane SCHEMBL10830357 | 0.83 | LMNA (0.50) | LMNATSHR | |
| Butane SCHEMBL3144035 | 0.83 | LMNA (0.50) | LMNA | |
| Propionaldehyde SCHEMBL8906570 | 0.81 | LMNA (0.60) | LMNATSHRTHRB | |
| Butane SCHEMBL8312214 | 0.81 | LMNA (0.60) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206205-B1 | PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND | PRIMEGENE BEIJING CO LTD (CN) | 2026-03-04 | — | — | EP | claimed |
| US-20250320221-A1 | NOVEL INTERMEDIATE, METHOD FOR PREPARING THE SAME AND APPLICATION THEREOF | UNIV SICHUAN (CN) | 2025-10-16 | — | — | US | claimed |
| EP-4613745-A2 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | Gilead Sciences, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| EP-4479405-A1 | SYNTHESIS OF BRUTON'S TYROSINE KINASE INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2024-12-25 | — | — | EP | claimed |
| US-11891375-B2 | Method for the synthesis of 2,4-dimethylpyrimidin-5-ol, intermediates, and method for the synthesis of Lemborexant using the intermediates | MOEHS IBERICA, S.L. (ES) | 2024-02-06 | — | — | US | claimed |
| US-20230303578-A1 | PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND | PRIMEGENE (BEIJING) CO., LTD. (CN) | 2023-09-28 | — | — | US | claimed |
| WO-2023156599-A1 | SYNTHESIS OF BRUTON'S TYROSINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-24 | — | — | WO | claimed |
| EP-4206205-A1 | PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND | Primegene (Beijing) Co., Ltd. (CN) | 2023-07-05 | — | — | EP | claimed |
| EP-4201926-A1 | NOVEL INTERMEDIATE, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | Sichuan University (CN) | 2023-06-28 | — | — | EP | claimed |
| CN-111620764-B | Selective ether bond cleavage method of aryl alkyl ether | 荆楚理工学院 | 2023-05-05 | — | — | CN | claimed |
| US-20080308426-A1 | Electrochemical Method for the Production of Betulin Aldehyde | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2008-12-18 | — | — | US | claimed |
| WO-2008039414-A1 | PROCESS FOR THE PREPARATION OF 4-HYDROXYTHIENO[2,3-B]PYRIDINE-5-CARBONITRILES | WYETH (US) | 2008-04-03 | — | — | WO | claimed |
| US-20080076926-A1 | Process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles | WYETH | 2008-03-27 | — | — | US | claimed |
| WO-2006105357-A2 | ELECTROCHEMICAL METHOD FOR THE PRODUCTION OF BETULIN ALDEHYDE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-10-05 | — | — | WO | claimed |
| WO-2006068410-A1 | NOVEL 3-(2-AMINO-6-PYRIDINYL)-4-HYDROXYPHENYL AMINE DERIVATIVES | LG LIFE SCIENCES, LTD. (KR) | 2006-06-29 | — | — | WO | claimed |
| US-5248760-A | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | UNC AT CHARLOTTE (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992013024-A1 | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 1992-08-06 | — | — | WO | claimed |
| EP-0132024-B1 | STABILISED FORMULATION SUITABLE FOR USE IN PYROLYTIC GLASS COATING PROCESS | M & T CHEMICALS, INC. (US) | 1987-09-30 | — | — | EP | claimed |
| US-4530857-A | Heating glass container; spraying with a monoalkyltin trihalide solution | M&T CHEMICALS INC. (US) | 1985-07-23 | — | — | US | claimed |
| EP-0132024-A2 | Stabilised formulation suitable for use in pyrolytic glass coating process | M & T CHEMICALS, INC. (US) | 1985-01-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891375-B2 | Method for the synthesis of 2,4-dimethylpyrimidin-5-ol, intermediates, and method for the synthesis of Lemborexant using the intermediates | NISCH, DDO, NNT | LMNA 662/4885TSHR 3826/4885THRB 3368/4885 |
| US-20230303578-A1 | PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND | DPYD, RPLP2, DHPS | LMNA 4225/4885TSHR 4332/4885THRB 4571/4885 |
| US-20080076926-A1 | Process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles | MAP4K2, MAP4K1, MAP4K3 | LMNA 2773/4885TSHR 2160/4885THRB 978/4885 |
| US-20250320221-A1 | NOVEL INTERMEDIATE, METHOD FOR PREPARING THE SAME AND APPLICATION THEREOF | OPRK1, OPRM1, OPRD1 | LMNA 4807/4885TSHR 4223/4885THRB 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.