Sugi Predict

Sugi Predict / Compounds / SCHEMBL134677

SCHEMBL134677

SCHEMBL134677

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc4c5c(ccc-3c25)-c2c-4c(-c3ccccc3)c3cc(N(c4ccccc4)c4ccccc4)ccc3c2-c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ THRB P10828 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ ABCB1 P08183 2/20 0.32
▸ ATM Q13315 2/20 0.31
▸ CRHBP P24387 1/20 0.31
▸ CRHR2 Q13324 1/20 0.31
▸ TLR9 Q9NR96 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25693027 0.97 TDP1 (0.33) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL20149204 0.89 MAPK14 (0.33) TDP1MAPTKDM4EMEN1KMT2A
SCHEMBL26336634 0.89 L3MBTL1 (0.41) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL15097041 0.88 TDP1 (0.32) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL12021431 0.87 ALDH1A1 (0.34) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL36956 0.87 L3MBTL1 (0.42) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL13777117 0.87 ALDH1A1 (0.42) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL4650027 0.87 L3MBTL1 (0.42) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL12239139 0.87 ALDH1A1 (0.36) TDP1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL26336635 0.86 TDP1 (0.34) TDP1ALDH1A1L3MBTL1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 — — US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 — — US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 — — US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 — — US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 — — US disclosed
US-20120056172-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-03-08 — — US disclosed
US-20120056172-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-03-08 — — US disclosed
US-8084147-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2011-12-27 — — US disclosed
US-8084147-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2011-12-27 — — US disclosed
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-08-25 — — US disclosed
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-08-25 — — US disclosed
US-7960041-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-06-14 — — US disclosed
US-7960041-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-06-14 — — US disclosed
EP-2121547-B1 ORGANIC LIGHT-EMITTING DEVICE CANON KK (JP) 2011-01-12 — — EP disclosed
EP-2054360-B1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KK (JP) 2010-11-10 — — EP disclosed
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-12-03 — — US disclosed
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-12-03 — — US disclosed
US-20090278446-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-11-12 — — US disclosed
US-20090278446-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-11-12 — — US disclosed
WO-2008111540-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2008-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090295279-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME ARL1, TYR, OR10J3 TDP1 4023/4885ALDH1A1 672/4885L3MBTL1 442/4885
US-20110204352-A1 FUSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME ARL1, TYR, OR10J3 TDP1 4023/4885ALDH1A1 672/4885L3MBTL1 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.