SCHEMBL20149204

SCHEMBL20149204

Cc1ccccc1-c1c2c(c(-c3ccccc3C)c3ccccc13)-c1ccc3c4c(ccc-2c14)-c1c-3c(-c2ccccc2)c2cc(N(c3ccccc3)c3ccccc3)ccc2c1-c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.33
KDM4E B2RXH2 1/20 0.32
RPA1 P27694 1/20 0.31
MCL1 Q07820 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ABCB1 P08183 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134677 0.89 TDP1 (0.35) KDM4EMEN1THRBRECQLBLM
SCHEMBL25693027 0.87 TDP1 (0.33) KDM4EMEN1THRBRECQLBLM
SCHEMBL22328882 0.86
SCHEMBL23806086 0.86 KDM4E (0.33) KDM4ETDP1MAPT
SCHEMBL23806006 0.85 LCK (0.36) MEN1THRBRECQLKMT2ATDP1
SCHEMBL23764464 0.82 MCL1 (0.35) MAPK14KDM4ERPA1MCL1MAPT
SCHEMBL12021431 0.81 ALDH1A1 (0.34) KDM4EMCL1MEN1THRBKMT2A
SCHEMBL12239139 0.80 ALDH1A1 (0.36) KDM4EMCL1TDP1MAPT
SCHEMBL20149195 0.80
SCHEMBL26336634 0.79 L3MBTL1 (0.41) KDM4EMEN1THRBRECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11128791-B2 Photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-11121182-B2 Organic photoelectric conversion element, optical area sensor, image pickup device, and image pickup apparatus CANON KABUSHIKI KAISHA (JP) 2021-09-14 US disclosed
US-10468614-B2 Photoelectric conversion element, image pick-up element, and image pick-up apparatus CANON KABUSHIKI KAISHA (JP) 2019-11-05 US disclosed
US-20190267411-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20180138432-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICK-UP ELEMENT, AND IMAGE PICK-UP APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-05-17 US disclosed
US-20180138432-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICK-UP ELEMENT, AND IMAGE PICK-UP APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CPNE4, LEF1, EMC1 MAPK14 1096/4885KDM4E 2038/4885RPA1 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.