SCHEMBL1346900

SCHEMBL1346900

CN(C)c1ccc(C2(c3cccn3C)OC(=O)c3cc(N(C)C)ccc32)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
TDP1 Q9NUW8 4/20 0.72
CYP3A4 P08684 2/20 0.72
HSD17B10 Q99714 2/20 0.72
HPGD P15428 2/20 0.72
HIF1A Q16665 1/20 0.72
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
LMNA P02545 4/20 0.35
MAPT P10636 4/20 0.35
POLB P06746 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GPR55 Q9Y2T6 2/20 0.35
ESR1 P03372 1/20 0.35
TP53 P04637 1/20 0.35
TYMS P04818 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27628798 0.94 ALDH1A1 (0.63) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL11651765 0.90 TDP1 (0.58) ALDH1A1TDP1CYP3A4HSD17B10HPGD
Indole SCHEMBL9707209 0.87 ALDH1A1 (0.55) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL4787639 0.85 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL27188 0.85 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL18143522 0.85 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL1446856 0.81 ALDH1A1 (0.76) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL29791059 0.81 ALDH1A1 (0.76) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL11259358 0.81 TDP1 (0.48) ALDH1A1TDP1CYP3A4HSD17B10HPGD
SCHEMBL11199311 0.80 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US claimed
US-7501172-B2 Integrated recording and labeling with optical recording device HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-03-10 US claimed
US-20080248950-A1 Ink and Developer System DAYTON REGION SIGNATURE FUND L.P. 2008-10-09 US claimed
US-7172991-B2 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-02-06 US claimed
US-20060262178-A1 Integrated recording and labeling with optical recording device ANDERSON DARYL E 2006-11-23 US claimed
US-20030108708-A1 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. 2003-06-12 US claimed
EP-3395583-B1 HEAT-SENSITIVE RECORDING MATERIAL NIPPON KAYAKU KK (JP) 2024-03-27 EP disclosed
EP-4205990-A1 THERMOSENSITIVE RECORDING MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2023-07-05 EP disclosed
WO-2023100900-A1 THERMAL RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2023100902-A1 HEAT-SENSITIVE RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
CN-111619258-B Thermosensitive recording material and preparation method thereof 乐凯医疗科技有限公司 2021-10-19 CN disclosed
US-10899153-B2 Heat-sensitive recording material and diphenylsulfone NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2021-01-26 US disclosed
US-10780724-B2 Heat-sensitive recording material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2020-09-22 US disclosed
US-3963553-A NAPHTHALENESULFONIC ACID-FORMALDEHYDE CONDENSATION PRODUCT FUJI PHOTO FILM CO., LTD. (JA) 1976-06-15 US disclosed
US-3960638-A ADHESIVE, NAPHTHALENE SULFONIC ACID FORMALDEHYDE CONDENSATION PRODUCT, POLYMER, METAL SALT FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US disclosed
US-3955025-A Pressure-sensitive copying sheet FUJI PHOTO FILM CO., LTD. (JA) 1976-05-04 US disclosed
US-3955026-A Pressure-sensitive recording sheet FUJI PHOTO FILM CO., LTD. (JA) 1976-05-04 US disclosed
US-3952117-A COLOR DEVELOPER, POLYOXYPROPYLENE GLYCOL FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3952129-A AROMATIC SECONDARY AMINE FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10780724-B2 Heat-sensitive recording material KCNH2, KCNH3, TRPA1 ALDH1A1 673/4885TDP1 3832/4885CYP3A4 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.