SCHEMBL13469110

SCHEMBL13469110

CCc1ccccc1C(=O)N1CCSCC1C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CNR2 P34972 2/20 0.38
CNR1 P21554 1/20 0.38
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
POLB P06746 2/20 0.36
HCRTR1 O43613 4/20 0.36
HCRTR2 O43614 4/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
GFER P55789 1/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP7 P09237 1/20 0.35
MMP13 P45452 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13469115 0.89 MEN1 (0.45) NPSR1HSD17B10KMT2AMEN1POLB
SCHEMBL20366875 0.85 NPSR1 (0.52) NPSR1HSD17B10CNR2CNR1KMT2A
SCHEMBL15614470 0.83 NPSR1 (0.47) NPSR1HSD17B10CNR2CNR1KMT2A
SCHEMBL13469109 0.81 CNR2 (0.53) CNR2CNR1KMT2AMEN1TSHR
SCHEMBL13469107 0.81 CNR1 (0.50) CNR2CNR1KMT2AMEN1TSHR
SCHEMBL20366905 0.79 NR1D1 (0.46) NPSR1HSD17B10KMT2AMEN1CYP2C19
SCHEMBL15614471 0.76 NR1D1 (0.41) NPSR1HSD17B10KMT2AMEN1POLB
SCHEMBL14280059 0.73 KMT2A (0.56) KMT2ACYP1A2CYP2C19ALDH1A1GAA
SCHEMBL13469117 0.71 ALDH1A1 (0.54) NPSR1KMT2AMEN1POLBTSHR
SCHEMBL23884759 0.70 HSD17B10 (0.41) NPSR1HSD17B10HCRTR1HCRTR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016008862-A1 SUBSTITUTED VINYL AND ALKYNYL CYANOCYCLOALKANOLS AND VINYL AND ALKYNYL CYANOHETEROCYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-21 WO disclosed
WO-2012139891-A1 SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-10-18 WO disclosed