Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20366905 | 0.89 | NR1D1 (0.46) | MEN1KMT2AKDM4ENR1D1ALDH1A1 | |
| SCHEMBL13469110 | 0.89 | NPSR1 (0.47) | MEN1KMT2APOLBALDH1A1TSHR | |
| SCHEMBL15614471 | 0.86 | NR1D1 (0.41) | MEN1KMT2APOLBKDM4ENR1D1 | |
| SCHEMBL14280059 | 0.84 | KMT2A (0.56) | KMT2AKDM4ENR1D1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13469117 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2APOLBKDM4ENR1D1 | |
| SCHEMBL13469108 | 0.81 | KDM4E (0.54) | MEN1KMT2APOLBKDM4ENR1D1 | |
| SCHEMBL20366875 | 0.77 | NPSR1 (0.52) | KMT2APOLBALDH1A1TSHRNPSR1 | |
| SCHEMBL10947045 | 0.76 | GAA (0.58) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL30177262 | 0.76 | CYP4F2 (0.47) | MEN1KMT2APOLBKDM4ENR1D1 | |
| SCHEMBL25718953 | 0.76 | CYP4F2 (0.47) | MEN1KMT2APOLBKDM4ENR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016008862-A1 | SUBSTITUTED VINYL AND ALKYNYL CYANOCYCLOALKANOLS AND VINYL AND ALKYNYL CYANOHETEROCYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-21 | — | — | WO | disclosed |
| WO-2012139891-A1 | SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2012-10-18 | — | — | WO | disclosed |