Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 1.00 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 1.00 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 1.00 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | SLC28A1 | O00337 | 1/20 | 1.00 |
| ▸ | MAP3K7 | O43318 | 1/20 | 1.00 |
| ▸ | SLC28A2 | O43868 | 1/20 | 1.00 |
| ▸ | GAPDH | P04406 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | PI4KA | P42356 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 1.00 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 1.00 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 1.00 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL12352425 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL1821276 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL4522263 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL13362239 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL24538665 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2228590 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23804425 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL406207 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23420216 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2403819 | 1.00 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116500105-A | Electrochemical aptamer sensor for detecting adenosine and preparation method and application thereof | 华东理工大学 | 2023-07-28 | — | — | CN | claimed |
| WO-2023077013-A1 | ENGINEERED RNAS | SHAPE THERAPEUTICS INC. (US) | 2023-05-04 | — | — | WO | claimed |
| CN-113834927-A | Salivary metabolism marker for predicting canceration of oral mucosa precancerous lesion patient and application thereof | 南京市口腔医院 | 2021-12-24 | — | — | CN | claimed |
| WO-2019174560-A1 | COMPOSITION FOR PURIFICATION OF BIOFLUIDS | 必康生技（香港）有限公司 | 2019-09-19 | — | — | WO | claimed |
| US-20190003966-A1 | Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy | SENA RESEARCH, INCORPORATED (US) | 2019-01-03 | — | — | US | claimed |
| US-20130183765-A1 | Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy | Sena Research Incorporated (US) | 2013-07-18 | — | — | US | claimed |
| WO-2012037158-A2 | ULTRAVIOLET AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHODS FOR THE EVALUATION OF SUNSCREEN EFFICACY | SENA RESEARCH, INCORPORATED (US) | 2012-03-22 | — | — | WO | claimed |
| WO-2011130385-A1 | BIOMARKERS FOR HEPATOCELLULAR CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC | 2011-10-20 | — | — | WO | claimed |
| EP-2313521-A2 | GENETIC VARIATIONS ASSOCIATED WITH FEATHER PECKING BEHAVIOUR IN AVIANS | Lohmann Tierzucht GmbH (DE) | 2011-04-27 | — | — | EP | claimed |
| EP-2208510-B1 | Cosmetic or dermatological composition comprising a retinoid, a non-phosphated compound based on adenosine and a semi-crystalline polymer | OREAL (FR) | 2011-03-30 | — | — | EP | claimed |
| EP-2151502-A1 | Genetic variations associated with feather pecking behaviour in avians | Lohmann Tierzucht GmbH (DE) | 2010-02-10 | — | — | EP | claimed |
| WO-2010012476-A2 | GENETIC VARIATIONS ASSOCIATED WITH FEATHER PECKING BEHAVIOUR IN AVIANS | LOHMANN TIERZUCHT GMBH (DE) | 2010-02-04 | — | — | WO | claimed |
| CN-116500105-A | Electrochemical aptamer sensor for detecting adenosine and preparation method and application thereof | 华东理工大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-116500105-A | Electrochemical aptamer sensor for detecting adenosine and preparation method and application thereof | 华东理工大学 | 2023-07-28 | — | — | CN | disclosed |
| WO-2023077013-A1 | ENGINEERED RNAS | SHAPE THERAPEUTICS INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-113514531-B | Fragment ion prediction method and application of compound | 清华大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-1102186-A | Determination and usage of new component of traditional Chinese medicine Chinese onion | SHENYANG MEDICAL COLLEGE (CN) | 1995-05-03 | — | — | CN | disclosed |
| WO-1994002497-A1 | SULFO-DERIVATIVES OF ADENOSINE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-03 | — | — | WO | disclosed |
| US-5116741-A | Subtilisin catalyzed acylation of nucleosides | GENEX CORPORATION (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0191869-A1 | FISH CALCITONIN DERIVATIVE, PROCESS FOR ITS PREPARATION, AND GENE SYSTEM THEREFOR | HODOGAYA CHEMICAL COMPANY, LIMITED (JP) | 1986-08-27 | — | — | EP | disclosed |