Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797717 | 0.93 | PLA2G4B (0.55) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL6231558 | 0.93 | PLA2G4B (0.55) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL9797915 | 0.93 | PLA2G4B (0.55) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL21990 | 0.93 | PLA2G4B (0.55) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL382120 | 0.93 | PLA2G4B (0.55) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL1496573 | 0.86 | LMNA (0.56) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL7804281 | 0.86 | LMNA (0.56) | S1PR1PLA2G4BLMNATSHRPOLB | |
| SCHEMBL588614 | 0.82 | ABCB1 (0.63) | S1PR1PLA2G4BLMNATSHRCYP2D6 | |
| SCHEMBL588999 | 0.82 | ABCB1 (0.63) | S1PR1PLA2G4BLMNATSHRCYP2D6 | |
| SCHEMBL6836270 | 0.82 | ABCB1 (0.63) | S1PR1PLA2G4BLMNATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062845-B2 | Rapid nucleic acid isolation method and compositions | CREIGHTON UNIVERSITY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20070077562-A1 | Rapid nucleic acid isolation method and compositions | CREIGHTON UNIVERSITY | 2007-04-05 | — | — | US | disclosed |
| WO-2005010204-A2 | RAPID NUCLEIC ACID ISOLATION METHOD AND COMPOSITIONS THEREFORE | CREIGHTON UNIVERSITY (US) | 2005-02-03 | — | — | WO | disclosed |
| US-5370773-A | Creping adhesives | JAMES RIVER CORPORATION OF VIRGINIA (US) | 1994-12-06 | — | — | US | disclosed |
| US-4447570-A | DISPOSABLE DIAPER INTERLINERS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1984-05-08 | — | — | US | disclosed |