Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368502 | 0.98 | ALDH1A1 (0.35) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL24369027 | 0.97 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL24368497 | 0.97 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL24368694 | 0.97 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL13475674 | 0.89 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL24369029 | 0.89 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL24368509 | 0.88 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL12762129 | 0.88 | ACHE (0.33) | ESR1ESR2 | |
| SCHEMBL24368696 | 0.88 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL24368695 | 0.87 | ESR1 (0.35) | ESR1ESR2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817272-B1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2010-02-03 | — | — | EP | disclosed |
| US-20080125609-A1 | Compounds for Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | US | disclosed |
| US-20080125609-A1 | Compounds for Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125609-A1 | Compounds for Organic Electronic Devices | PIEZO1, ETV6, OR10J3 | ESR1 5/4885ESR2 49/4885KDM4E 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.