Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449223 | 0.94 | NAAA (0.52) | NAAATHRBHTTCYP2C19CYP19A1 | |
| SCHEMBL25239579 | 0.91 | NAAA (0.50) | NAAATHRBHTTCYP2C19CYP19A1 | |
| SCHEMBL27818005 | 0.89 | NAAA (0.49) | NAAATHRBHTTCYP2C19CYP19A1 | |
| SCHEMBL12360321 | 0.88 | THRB (0.38) | NAAATHRBHTTCYP19A1TSHR | |
| SCHEMBL11509591 | 0.86 | THRB (0.49) | NAAATHRBHTTCYP2C19CYP19A1 | |
| SCHEMBL13475738 | 0.82 | THRB (0.38) | NAAATHRBHTTTSHRALDH1A1 | |
| SCHEMBL21420092 | 0.81 | NAAA (0.45) | NAAATHRBHTTCYP2C19CYP19A1 | |
| SCHEMBL13475743 | 0.81 | THRB (0.39) | NAAATHRBHTTTSHRALDH1A1 | |
| SCHEMBL13475730 | 0.81 | THRB (0.39) | NAAATHRBHTTTSHRALDH1A1 | |
| SCHEMBL16744077 | 0.80 | THRB (0.61) | THRBHTTTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928929-B1 | CURABLE COMPOSITIONS CONTAINING DITHIANE MONOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2010-02-17 | — | — | EP | disclosed |
| US-7495054-B2 | Curable compositions containing dithiane monomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495054-B2 | Curable compositions containing dithiane monomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-02-24 | — | — | US | disclosed |
| WO-2007035735-A1 | CURABLE COMPOSITIONS CONTAINING DITHIANE MONOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-03-29 | — | — | WO | disclosed |
| US-20070066748-A1 | Curable compositions containing dithiane monomers | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-22 | — | — | US | disclosed |
| US-20070066748-A1 | Curable compositions containing dithiane monomers | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-22 | — | — | US | disclosed |