Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13476327 | 0.92 | SIGMAR1 (0.34) | MEN1KMT2ACYP2D6HPGDCYP3A4 | |
| SCHEMBL13476296 | 0.92 | SIGMAR1 (0.34) | MEN1KMT2ACYP2D6HPGDCYP3A4 | |
| SCHEMBL2157532 | 0.90 | PRKCA (0.36) | GAAHPGDPKMKDM4EALDH1A1 | |
| SCHEMBL13476294 | 0.90 | ACKR3 (0.41) | ALDH1A1 | |
| SCHEMBL13476318 | 0.88 | L3MBTL1 (0.38) | KMT2AGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13476330 | 0.86 | CNR2 (0.36) | KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL13476329 | 0.85 | TP53 (0.40) | MEN1KMT2ACYP2D6KDM4EALDH1A1 | |
| SCHEMBL13476295 | 0.85 | ACKR3 (0.39) | MEN1KMT2A | |
| SCHEMBL13476328 | 0.85 | KCNH2 (0.34) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13476299 | 0.84 | TSHR (0.36) | KMT2AGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659263-B2 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-02-09 | — | — | US | disclosed |