SCHEMBL13476352

SCHEMBL13476352

COc1ccc(C(=O)Oc2ccc(C=O)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.69
MAPT P10636 6/20 0.69
GFER P55789 1/20 0.69
ALDH1A1 P00352 5/20 0.66
CYP2A6 P11509 1/20 0.66
LMNA P02545 4/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
PRSS1 P07477 1/20 0.56
ACR P10323 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
MEN1 O00255 1/20 0.56
KDM4E B2RXH2 2/20 0.55
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.52
F3 P13726 1/20 0.51
CES2 O00748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14513468 1.00 KMT2A (0.69) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL15500749 1.00 KMT2A (0.69) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL27444698 0.91 MAPT (0.59) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL9400232 0.91 KMT2A (0.63) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL4243129 0.91 KMT2A (0.63) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL18906001 0.90 KMT2A (0.58) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL15373867 0.90 ALDH1A1 (0.79) KMT2AMAPTGFERALDH1A1CYP2A6
Benzaldehyde SCHEMBL7545226 0.89 KMT2A (0.59) KMT2AMAPTGFERALDH1A1CYP2A6
SCHEMBL9666088 0.87 LMNA (0.75) KMT2AMAPTGFERALDH1A1LMNA
SCHEMBL12608584 0.87 LMNA (0.75) KMT2AMAPTGFERALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005478-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT DISPLAYS INCORPORATED (US) 2015-04-14 US disclosed
US-9005478-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT DISPLAYS INCORPORATED (US) 2015-04-14 US disclosed
US-9005478-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT DISPLAYS INCORPORATED (US) 2015-04-14 US disclosed
US-20140117284-A1 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2014-05-01 US disclosed
US-8709281-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT STATE UNIVERSITY (US) 2014-04-29 US disclosed
US-8709281-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT STATE UNIVERSITY (US) 2014-04-29 US disclosed
US-8709281-B2 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays KENT STATE UNIVERSITY (US) 2014-04-29 US disclosed
US-8691111-B2 Tetraoxybiphenyl ester chiral dopants for cholesteric liquid crystal displays KENT DISPLAYS INC. (US) 2014-04-08 US disclosed
US-8691111-B2 Tetraoxybiphenyl ester chiral dopants for cholesteric liquid crystal displays KENT DISPLAYS INC. (US) 2014-04-08 US disclosed
US-20140054498-A1 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2014-02-27 US disclosed
US-20140054498-A1 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2014-02-27 US disclosed
US-20140054498-A1 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2014-02-27 US disclosed
WO-2012149124-A2 TETRAOXYBIPHENYL ESTER CHIRAL DOPANTS FOR CHOLESTERIC LIQUID CRYSTAL DISPLAYS KENT DISPLAYS INCORPORATED (US) 2012-11-01 WO disclosed
US-20120273725-A1 Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2012-11-01 US disclosed
US-20120273725-A1 Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2012-11-01 US disclosed
US-20120273725-A1 Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays KENT STATE UNIVERSITY (US) 2012-11-01 US disclosed
US-20100025641-A1 INFRARED REGION SELECTIVE REFLECTION COAT AND INFRARED REGION SELECTIVE REFLECTION FILM FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140054498-A1 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays DHCR7, NR1H4, CYP46A1 KMT2A 2162/4885MAPT 2861/4885GFER 3611/4885
US-20120273725-A1 Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays DHCR7, CYP7A1, CCR7 KMT2A 3175/4885MAPT 2327/4885GFER 713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.