Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 9/20 | 0.54 |
| ▸ | MC4R | P32245 | 6/20 | 0.53 |
| ▸ | MC5R | P33032 | 2/20 | 0.53 |
| ▸ | MC3R | P41968 | 2/20 | 0.53 |
| ▸ | MC1R | Q01726 | 2/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13144545 | 0.96 | MC4R (0.55) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13478177 | 0.96 | MC4R (0.55) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13144540 | 0.95 | MC4R (0.53) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13144542 | 0.94 | IL23R (0.54) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13144549 | 0.93 | KISS1R (0.54) | IL23RMC4RCXCR4OPRM1OPRK1 | |
| SCHEMBL13144631 | 0.93 | MC4R (0.53) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13144378 | 0.92 | IL23R (0.53) | IL23RMC4RMC5RMC3RMC1R | |
| SCHEMBL13144534 | 0.89 | OPRM1 (0.61) | OPRM1OPRK1 | |
| SCHEMBL13144373 | 0.89 | CXCL8 (0.49) | IL23RC5AR1 | |
| SCHEMBL13145223 | 0.88 | MC4R (0.50) | IL23RMC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659246-B2 | Treatment of osteoarthritis | PROMICS PTY LIMITED (AU) | 2010-02-09 | — | — | US | disclosed |