Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 13/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.52 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600 | 0.85 | OPRM1 (0.42) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL18597715 | 0.84 | LPAR1 (0.58) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL9939475 | 0.81 | LPAR1 (0.54) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL9939476 | 0.81 | LPAR1 (0.54) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL18746088 | 0.81 | LPAR1 (0.52) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL6283 | 0.80 | LPAR1 (0.52) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL14794645 | 0.80 | LPAR1 (0.53) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL6556 | 0.79 | LPAR1 (0.51) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL6674 | 0.79 | LPAR1 (0.53) | LPAR1CYP2C9ABCC3ABCC4ABCB11 | |
| SCHEMBL18597706 | 0.79 | LPAR1 (0.63) | LPAR1CYP2C9ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041462-A2 | POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |