Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.63 |
| ▸ | MEN1 | O00255 | 11/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265371 | 0.82 | KMT2A (0.58) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL8350627 | 0.80 | SMN1; SMN2 (0.70) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL1951110 | 0.79 | GAA (0.61) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11911371 | 0.79 | ITGB3 (0.70) | KMT2AMEN1GAAPOLBRAB9A | |
| SCHEMBL6857302 | 0.77 | KMT2A (0.65) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL8179307 | 0.77 | KMT2A (0.52) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL2433522 | 0.77 | CASR (0.67) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL13480553 | 0.77 | TAS1R3 (0.60) | KMT2AMEN1GAARAB9ANPC1 | |
| SCHEMBL13480592 | 0.77 | GAA (0.59) | GAAPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13480591 | 0.77 | GAA (0.59) | KMT2AMEN1GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | disclosed |