Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279096 | 0.85 | GAA (0.51) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL13235126 | 0.82 | HTT (0.81) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL1951110 | 0.80 | GAA (0.61) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL11911371 | 0.80 | ITGB3 (0.70) | GAAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14295570 | 0.79 | ALDH1A1 (0.73) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL27953196 | 0.79 | CFD (0.67) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL4893345 | 0.79 | HTT (0.58) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL10906283 | 0.79 | HTT (0.69) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL15196083 | 0.79 | GAA (0.59) | GAARAB9ANPC1LMNAPOLB | |
| SCHEMBL13480553 | 0.79 | TAS1R3 (0.60) | GAAHTTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952244-A | PGD 2The N of acceptor, N-disubstituted amido alkyl biphenyl antagonist | AMIRA PHARMACEUTICALS INC | 2011-01-19 | — | — | CN | disclosed |
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | disclosed |