Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.31 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195130 | 0.81 | ADRB2 (0.35) | — | |
| SCHEMBL13484293 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL13484328 | 0.73 | TSHR (0.46) | — | |
| SCHEMBL13484283 | 0.73 | CYP2D6 (0.35) | — | |
| SCHEMBL17429845 | 0.73 | FAAH (0.32) | — | |
| SCHEMBL13484284 | 0.72 | — | — | |
| SCHEMBL13848516 | 0.72 | S1PR1 (0.39) | — | |
| SCHEMBL13744676 | 0.72 | S1PR1 (0.39) | CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL13484329 | 0.72 | HSP90AA1 (0.37) | — | |
| SCHEMBL13484017 | 0.72 | ENPP3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |
| EP-2093220-A2 | Inhibitors of fatty acid amide hydrolase | The Scripps Research Institute (US) | 2009-08-26 | — | — | EP | disclosed |