Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484115 | 0.82 | CYP1A2 (0.50) | NQO2CYP1A2CYP2A6MAOBCYP1A1 | |
| SCHEMBL7345665 | 0.77 | RELA (0.49) | NQO2CYP1A2CYP2A6MAOBCYP1A1 | |
| SCHEMBL21470094 | 0.77 | MAOB (0.49) | NQO2CYP1A2CYP2A6MAOBKDM4E | |
| SCHEMBL14325968 | 0.77 | MAOB (0.46) | NQO2CYP1A2CYP2A6MAOBCYP1A1 | |
| SCHEMBL7158461 | 0.73 | MAPT (0.72) | NQO2CYP1A2CYP2A6KDM4ELMNA | |
| SCHEMBL29818623 | 0.73 | EGFR (0.56) | CYP1A2MAOBNFE2L2KDM4ELMNA | |
| SCHEMBL14303313 | 0.73 | EGFR (0.56) | CYP1A2MAOBNFE2L2KDM4ELMNA | |
| SCHEMBL28673144 | 0.73 | EGFR (0.56) | CYP1A2MAOBNFE2L2KDM4ELMNA | |
| SCHEMBL9443956 | 0.72 | CYP1A2 (0.56) | NQO2CYP1A2CYP2A6MAOBCYP1A1 | |
| SCHEMBL12732162 | 0.72 | MAPT (0.50) | MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337941-B2 | Fluorescent substrates for monoamine transporters as optical false neurotransmitters | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100035279-A1 | Fluorescent Substrates for Monoamine Transporters as Optical False Neurotransmitters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035279-A1 | Fluorescent Substrates for Monoamine Transporters as Optical False Neurotransmitters | SLC18A2, SLC6A2, SLC18A3 | NQO2 248/4885CYP1A2 1053/4885CYP2A6 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.