Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484115 | 0.83 | CYP1A2 (0.50) | RELACYP1A2CYP2A6NQO2KDM4E | |
| SCHEMBL7343816 | 0.81 | ABL1 (0.37) | RELANQO2KDM4ECYP1A1PTGS2 | |
| SCHEMBL7336089 | 0.80 | PLAU (0.59) | RELACYP1A2CYP2A6NQO2KDM4E | |
| SCHEMBL7343141 | 0.80 | PLAU (0.59) | RELACYP1A2CYP2A6NQO2KDM4E | |
| SCHEMBL7334386 | 0.78 | PLAU (0.44) | RELACYP1A2CYP2A6NQO2MAOB | |
| SCHEMBL7334384 | 0.78 | PLAU (0.44) | RELACYP1A2CYP2A6NQO2MAOB | |
| SCHEMBL7158461 | 0.77 | MAPT (0.72) | CYP1A2CYP2A6NQO2KDM4ELMNA | |
| SCHEMBL21470094 | 0.77 | MAOB (0.49) | CYP1A2CYP2A6NQO2KDM4ELMNA | |
| SCHEMBL14325968 | 0.77 | MAOB (0.46) | CYP1A2CYP2A6NQO2KDM4ECYP1A1 | |
| SCHEMBL13484378 | 0.77 | NQO2 (0.45) | RELACYP1A2CYP2A6NQO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |