Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484296 | 0.86 | FAAH (0.36) | FAAHCYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL13484327 | 0.80 | FAAH (0.37) | FAAHCYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL13484390 | 0.79 | FAAH (0.46) | FAAH | |
| SCHEMBL13745032 | 0.78 | FAAH (0.42) | FAAHCYP2D6 | |
| SCHEMBL13484388 | 0.75 | FAAH (0.36) | FAAH | |
| SCHEMBL13484283 | 0.73 | CYP2D6 (0.35) | CYP2D6CYP19A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL13484012 | 0.72 | CYP1A2 (0.40) | FAAHCYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL13744919 | 0.71 | HPGDS (0.32) | — | |
| SCHEMBL13484389 | 0.70 | NOTUM (0.49) | FAAHCYP2C9CYP2C19KDM4E | |
| SCHEMBL13484392 | 0.70 | ADRB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |