Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577651 | 0.79 | MAPT (0.44) | GPR35DAOALDH1A1KDM4EMEN1 | |
| SCHEMBL23459994 | 0.76 | GPR35 (0.50) | GPR35DAOALDH1A1KDM4EMEN1 | |
| SCHEMBL13484580 | 0.72 | GAA (0.45) | ALDH1A1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL29953733 | 0.71 | GPR35 (0.46) | GPR35DAOALDH1A1KDM4EMEN1 | |
| SCHEMBL577650 | 0.69 | MAPT (0.45) | ALDH1A1KDM4EMAPTKMT2ANPC1 | |
| SCHEMBL17203079 | 0.69 | GSK3B (0.52) | GSK3BALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL8928677 | 0.67 | KMT2A (0.39) | GSK3BALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL30020630 | 0.66 | GPR35 (0.48) | GSK3BGPR35DAOALDH1A1KDM4E | |
| SCHEMBL5154649 | 0.65 | GPR35 (0.52) | GPR35DAOALDH1A1KDM4EMEN1 | |
| SCHEMBL8497895 | 0.65 | NPC1 (0.43) | GSK3BDAOALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029752-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | FAS SECURED CREDITORS HOLDCO, LLC | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029752-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME | CYP3A7, DHCR7, CYP2A7 | GSK3B 4555/4885GPR35 25/4885DAO 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.