Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | DAO | P14920 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459994 | 0.85 | GPR35 (0.50) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL1561317 | 0.82 | OPRD1 (0.43) | ALDH1A1KDM4EMAPTCYP3A4HPGD | |
| SCHEMBL577651 | 0.80 | MAPT (0.44) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL8929358 | 0.74 | CYP3A4 (0.43) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5154649 | 0.73 | GPR35 (0.52) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL13484615 | 0.71 | GSK3B (0.40) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL3093344 | 0.70 | DAO (0.65) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL577650 | 0.69 | MAPT (0.45) | ALDH1A1KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL16334956 | 0.67 | DAO (0.50) | GPR35DAOALDH1A1MEN1KMT2A | |
| SCHEMBL6179820 | 0.65 | DAO (0.44) | GPR35DAOALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |