Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 4/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163377 | 0.78 | PARP1 (0.38) | — | |
| SCHEMBL9243589 | 0.72 | GRM5 (0.40) | GRM5ACVR1BMPR1AACVRL1CNR1 | |
| SCHEMBL10677511 | 0.71 | POLB (0.30) | ALDH1A1 | |
| SCHEMBL17704768 | 0.71 | POLB (0.42) | — | |
| SCHEMBL23907169 | 0.68 | MAPT (0.53) | GRM5ACVR1BMPR1AACVRL1CNR1 | |
| SCHEMBL22216285 | 0.68 | MAPT (0.53) | GRM5ACVR1BMPR1AACVRL1CNR1 | |
| SCHEMBL23907167 | 0.68 | MAPT (0.53) | GRM5ACVR1BMPR1AACVRL1CNR1 | |
| SCHEMBL12374718 | 0.67 | — | — | |
| SCHEMBL11515949 | 0.67 | POLB (0.44) | — | |
| SCHEMBL4605352 | 0.67 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100040548-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD (CN) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040548-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HAMP | GRM5 3538/4885ACVR1 4225/4885BMPR1A 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.