Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13486172 | 0.90 | KDM4A (0.48) | CYP11B2KDM4AKDM5AKDM4CKDM5B | |
| SCHEMBL6950354 | 0.78 | CYP11B2 (0.44) | CYP11B2KDM4AKDM5AKDM4CKDM5B | |
| SCHEMBL14701672 | 0.75 | CDK5 (0.40) | CDK5CDK5R1 | |
| SCHEMBL15236765 | 0.74 | CPB2 (0.40) | CDK5CDK5R1 | |
| SCHEMBL3273845 | 0.74 | CPB2 (0.40) | CDK5CDK5R1 | |
| SCHEMBL14653682 | 0.73 | CDK5 (0.34) | CDK5CDK5R1 | |
| SCHEMBL3201410 | 0.73 | KDM4A (0.42) | CYP11B2KDM4AKDM5AKDM4CKDM5B | |
| SCHEMBL14631087 | 0.71 | CPB2 (0.51) | CDK5CDK5R1 | |
| SCHEMBL14631086 | 0.71 | CPB2 (0.51) | CDK5CDK5R1 | |
| SCHEMBL14631015 | 0.71 | CPB2 (0.42) | CYP11B2KDM5ACDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041722-A1 | ORGANIC COMPOUNDS | HU QI-YING | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041722-A1 | ORGANIC COMPOUNDS | CYP11B1, CYP11B2, CYP21A2 | CYP11B2 2/4885KDM4A 2449/4885KDM5A 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.