SCHEMBL1348734

SCHEMBL1348734

CCOO[Si](OOCC)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.41
CA4 P22748 1/20 0.36
CHRNB2 P17787 2/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA7 P36544 2/20 0.33
CHRNA4 P43681 2/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 1/20 0.33
RELA Q04206 1/20 0.33
KCNA3 P22001 1/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1347262 0.96 LTA4H (0.41) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL3887627 0.90 LTA4H (0.37) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL5391039 0.78 LTA4H (0.43) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL766451 0.78 LTA4H (0.43) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL1609097 0.78 LTA4H (0.43) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL15653550 0.77 LTA4H (0.47) LTA4HCA4MAPTTSHRKCNA3
SCHEMBL1347951 0.76 CA4 (0.46) LTA4HCA4TSHRRELAKCNA3
SCHEMBL1698229 0.75 LTA4H (0.48) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL301726 0.74 LTA4H (0.50) LTA4HCA4MAPTTSHRKCNA3
SCHEMBL23494822 0.73 LTA4H (0.39) LTA4HCA4CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023102567-A2 GRAFTABLE BIOCIDAL LINKERS AND POLYMERS AND USES THEREOF DEBOGY MOLECULAR, INC. (US) 2023-06-08 WO claimed
US-8062699-B2 Applying a silicate polymer of trimethylethoxyorthosilicate substituted acrylate to damaged portions of the concrete structure KOREA ELECTRIC POWER CORPORATION (KR) 2011-11-22 US claimed
US-7670421-B2 Penetration reinforcing agent for preventing aging of concrete and process for preparing the same KOREA ELECTRIC POWER CORPORATION (KR) 2010-03-02 US claimed
US-20080131594-A1 Method for repairing aged reinforced concrete structure using surface-penetration reinforcing agent KOREA ELECTRIC POWER CORPORATION 2008-06-05 US claimed
US-20070213480-A1 Concrete reinforcing material for improving durability of concrete structure and process for preparing the same KOREA ELECTRONIC POWER CORPORATION 2007-09-13 US claimed
US-20070098911-A1 Penetration reinforcing agent for preventing aging of concrete and process for preparing the same KOREA ELECTRONIC POWER CORPORATION 2007-05-03 US claimed
WO-2023102567-A2 GRAFTABLE BIOCIDAL LINKERS AND POLYMERS AND USES THEREOF DEBOGY MOLECULAR, INC. (US) 2023-06-08 WO disclosed
US-8062699-B2 Applying a silicate polymer of trimethylethoxyorthosilicate substituted acrylate to damaged portions of the concrete structure KOREA ELECTRIC POWER CORPORATION (KR) 2011-11-22 US disclosed
US-7670421-B2 Penetration reinforcing agent for preventing aging of concrete and process for preparing the same KOREA ELECTRIC POWER CORPORATION (KR) 2010-03-02 US disclosed
US-20080131594-A1 Method for repairing aged reinforced concrete structure using surface-penetration reinforcing agent KOREA ELECTRIC POWER CORPORATION 2008-06-05 US disclosed
US-20070213480-A1 Concrete reinforcing material for improving durability of concrete structure and process for preparing the same KOREA ELECTRONIC POWER CORPORATION 2007-09-13 US disclosed
US-20070098911-A1 Penetration reinforcing agent for preventing aging of concrete and process for preparing the same KOREA ELECTRONIC POWER CORPORATION 2007-05-03 US disclosed