SCHEMBL134875

SCHEMBL134875

Fc1[c]ccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28538724 0.77 ALOX5 (0.44)
SCHEMBL433164 0.75 ALOX5 (0.42)
SCHEMBL433433 0.74 GRM2 (0.36)
SCHEMBL435211 0.74 AHR (0.48)
SCHEMBL5182079 0.73 AHR (0.40)
SCHEMBL922603 0.72 AR (0.42)
SCHEMBL15067608 0.72 TP53 (0.35)
SCHEMBL3465 0.72
SCHEMBL7861005 0.72
SCHEMBL3039 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6232 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238285-A1 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. 2024-07-18 US claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-115611856-B Piperidine derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-07-05 CN claimed
WO-2024120442-A1 PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) 2024-06-13 WO claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-117983306-A Catalyst containing PCCP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-20240140919-A1 MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 DENALI THERAPEUTICS INC. 2024-05-02 US claimed
WO-2024089191-A1 MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 WO claimed
US-11970485-B2 RET kinase inhibitors ELI LILLY AND COMPANY (US) 2024-04-30 US claimed
CN-111201245-B Compounds, compositions, and methods 戴纳立制药公司 2024-04-05 CN claimed
EP-0113509-A2 1,3-Bis(triazolyl)-2-amino-2-aryl-propane derivatives and pharmaceutical fungicidal compositions containing them Pfizer Limited (GB) 1984-07-18 EP claimed
EP-0110570-A2 Triazole antifungal agents Pfizer Limited (GB) 1984-06-13 EP claimed
EP-0106515-A2 Triazole anti-fungal agents Pfizer Limited (GB) 1984-04-25 EP claimed
EP-0104734-A1 Triazole antifungal agents Pfizer Limited (GB) 1984-04-04 EP claimed
EP-0097425-A2 Fungicidal or plant growth regulating triazolyl ethanols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-04 EP claimed
EP-0095828-A1 Antifungal triazolyl propanol derivatives Pfizer Limited (GB) 1983-12-07 EP claimed
EP-0094146-A1 Antifungal azolyl phenyl substituted alicyclic alcohols ZENECA LIMITED (GB) 1983-11-16 EP claimed
EP-0089100-A2 Azolyl derivatives as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-21 EP claimed
EP-0082340-A1 Microbicidal triazolyl-ethyl-ethers CIBA-GEIGY AG (CH) 1983-06-29 EP claimed
EP-0048548-A1 Pharmaceutical compositions of fungicidal triazole derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-31 EP claimed