Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861005 | 0.81 | — | — | |
| SCHEMBL3139514 | 0.80 | ALOX5 (0.47) | ALOX5TAAR1ESR2MAOBNOTUM | |
| SCHEMBL6402089 | 0.80 | TAAR1 (0.48) | TAAR1ESR2NOTUMIDO1 | |
| SCHEMBL5967311 | 0.80 | MAOA (0.40) | ALOX5TAAR1ESR2 | |
| SCHEMBL433164 | 0.80 | ALOX5 (0.42) | ALOX5MAOBNOTUMNPC1TP53 | |
| SCHEMBL694723 | 0.79 | ALDH1A1 (0.41) | ALOX5TAAR1ESR2NOTUMNPC1 | |
| SCHEMBL27338776 | 0.78 | ALOX5 (0.40) | ALOX5TAAR1ESR2NPC1RAB9A | |
| SCHEMBL23167350 | 0.77 | ACHE (0.43) | NOTUMNPC1TP53TSHRRAB9A | |
| SCHEMBL21224463 | 0.77 | TAAR1 (0.47) | ALOX5TAAR1ESR2MAOBBACE1 | |
| SCHEMBL134875 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473472-B | 2-aminoquinazoline derivatives as P70S6kinase inhibitors | 圣提内尔肿瘤学有限公司 | 2021-02-12 | — | — | CN | disclosed |