Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820349 | 0.87 | TDP1 (0.42) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL17432611 | 0.85 | TDP1 (0.42) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL11562786 | 0.85 | TDP1 (0.42) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL3207330 | 0.85 | TDP1 (0.43) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL7818425 | 0.82 | TDP1 (0.57) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL3094266 | 0.80 | TDP1 (0.44) | TDP1CTDSP1HPGDALDH1A1KDM4E | |
| SCHEMBL8566458 | 0.79 | HPGD (0.61) | TDP1HPGDALDH1A1KDM4ECYP4F2 | |
| SCHEMBL924887 | 0.79 | HPGD (0.61) | TDP1HPGDALDH1A1KDM4ECYP4F2 | |
| SCHEMBL8566461 | 0.79 | HPGD (0.61) | TDP1HPGDALDH1A1KDM4ECYP4F2 | |
| SCHEMBL7827096 | 0.78 | AR (0.48) | TDP1CTDSP1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | TDP1 2282/4885CTDSP1 3846/4885HPGD 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.