Sugi Predict

Sugi Predict / Compounds / SCHEMBL3207330

SCHEMBL3207330

SCHEMBL3207330

CCOC(=O)C1CNc2cccc(Br)c2O1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.43
▸ CTDSP1 Q9GZU7 1/20 0.43
▸ HPGD P15428 1/20 0.39
▸ CYSLTR2 Q9NS75 1/20 0.37
▸ CYSLTR1 Q9Y271 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.36
▸ BRD4 O60885 1/20 0.36
▸ CYP4F2 P78329 1/20 0.36
▸ CYP4A11 Q02928 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ POLB P06746 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ MAPT P10636 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ PDE4A P27815 1/20 0.34
▸ PDE4B Q07343 1/20 0.34
▸ PDE4C Q08493 1/20 0.34
▸ PDE4D Q08499 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820349 0.87 TDP1 (0.42) TDP1CTDSP1HPGDCYSLTR2CYSLTR1
SCHEMBL17432611 0.85 TDP1 (0.42) TDP1CTDSP1HPGDCYSLTR2CYSLTR1
SCHEMBL11562786 0.85 TDP1 (0.42) TDP1CTDSP1HPGDKDM4ETSHR
SCHEMBL13487592 0.85 TDP1 (0.43) TDP1CTDSP1HPGDCYSLTR2CYSLTR1
SCHEMBL3094266 0.82 TDP1 (0.44) TDP1CTDSP1HPGDCYSLTR2CYSLTR1
SCHEMBL7818425 0.82 TDP1 (0.57) TDP1CTDSP1HPGDKDM4EALDH1A1
SCHEMBL3355786 0.81 POLB (0.38) HPGDCYP4F2CYP4A11POLBKMT2A
SCHEMBL924887 0.79 HPGD (0.61) TDP1HPGDKDM4ECYP4F2CYP4A11
SCHEMBL8566458 0.79 HPGD (0.61) TDP1HPGDKDM4ECYP4F2CYP4A11
SCHEMBL8566461 0.79 HPGD (0.61) TDP1HPGDKDM4ECYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136577-A1 HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2025-05-01 — — US disclosed
EP-4472734-A1 HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS C4X Discovery Limited (GB) 2024-12-11 — — EP disclosed
CN-119095837-A Heterocyclic derivatives as MALT1 inhibitors 希四克斯探索有限公司 2024-12-06 — — CN disclosed
WO-2023148501-A1 HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2023-08-10 — — WO disclosed
US-20100035871-A1 BENZOXAZINE DERIVATIVES AND USES THEREOF WYETH 2010-02-11 — — US disclosed
US-20100035871-A1 BENZOXAZINE DERIVATIVES AND USES THEREOF WYETH 2010-02-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136577-A1 HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS MALT1, SQSTM1, FKBP1A TDP1 639/4885CTDSP1 4295/4885HPGD 2461/4885
US-20100035871-A1 BENZOXAZINE DERIVATIVES AND USES THEREOF HTR2C, HTR5A, NPY1R TDP1 2282/4885CTDSP1 3846/4885HPGD 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.