SCHEMBL13488293

SCHEMBL13488293

Cc1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccc4c(c3)N(C)c3ccccc3C4)c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
HTT P42858 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 1/20 0.34
GFER P55789 1/20 0.34
HTR2A P28223 3/20 0.34
HTR2C P28335 3/20 0.34
HRH1 P35367 3/20 0.34
PTGS2 P35354 2/20 0.33
DRD2 P14416 1/20 0.33
ADRA1A P35348 1/20 0.33
MAPK8 P45983 1/20 0.32
POLB P06746 1/20 0.32
ACHE P22303 2/20 0.32
LMNA P02545 2/20 0.32
BCHE P06276 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488300 0.99 HTR2A (0.35) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL13488282 0.93 HSD17B3 (0.38) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL13488287 0.92 HSD17B3 (0.39) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL13488295 0.90 AKT1 (0.38) ALDH1A1HSD17B10HPGDHTR2AHTR2C
SCHEMBL13488296 0.87 GPR84 (0.32) ALDH1A1KDM4EMEN1KMT2AHTR2A
SCHEMBL13488297 0.87 HTR2C (0.33) ALDH1A1KDM4EHTR2AHTR2CHRH1
SCHEMBL13488313 0.86 PTGS2 (0.38) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL13488590 0.85 HTR2A (0.32) HTR2AHTR2CHRH1DRD2ADRA1A
SCHEMBL13488319 0.84 PTGS2 (0.37) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL13487484 0.84 PDK2 (0.32) HTR2AHTR2CHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
EP-2108689-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 ALDH1A1 101/4885KDM4E 3671/4885HTT 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.