SCHEMBL13488295

SCHEMBL13488295

Cc1ccc2c(-c3ccc4ccccc4c3)c3ccccc3c(-c3ccc4c(c3)N(C)c3ccccc3C4)c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.38
CYP2A6 P11509 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR2A P28223 4/20 0.33
HTR2C P28335 2/20 0.33
HRH1 P35367 2/20 0.33
CYP1A2 P05177 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
IKBKB O14920 1/20 0.32
MAOA P21397 1/20 0.32
DRD2 P14416 3/20 0.32
DRD1 P21728 2/20 0.32
ADRA1A P35348 1/20 0.31
PTGER3 P43115 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488283 0.93 AKT1 (0.38) AKT1CYP2A6TDP1HTR2ACYP1A2
SCHEMBL13488293 0.90 ALDH1A1 (0.34) HTR2AHTR2CHRH1ALDH1A1HPGD
SCHEMBL13488300 0.88 HTR2A (0.35) HTR2AHTR2CHRH1ALDH1A1HPGD
SCHEMBL13488297 0.88 HTR2C (0.33) AKT1CYP2A6HTR2AHTR2CHRH1
SCHEMBL13488296 0.88 GPR84 (0.32) HTR2AHTR2CHRH1ALDH1A1SMN1; SMN2
SCHEMBL13488315 0.86 AKT1 (0.45) AKT1CYP2A6TDP1HTR2ACYP1A2
SCHEMBL13488325 0.83 MAOA (0.44) AKT1CYP2A6TDP1HTR2CCYP1A2
SCHEMBL13488282 0.82 HSD17B3 (0.38) ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10
SCHEMBL13488590 0.82 HTR2A (0.32) HTR2AHTR2CHRH1DRD2ADRA1A
SCHEMBL13426071 0.82 HTR3A (0.41) AKT1HTR2AHTR2CALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
EP-2108689-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 AKT1 4539/4885CYP2A6 1410/4885TDP1 1904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.