SCHEMBL1348889

SCHEMBL1348889

c1ccc(C(c2ccccc2)c2ncc[nH]2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.50
SLC6A4 P31645 4/20 0.50
SLC6A3 Q01959 3/20 0.50
MTOR P42345 1/20 0.50
ADK P55263 1/20 0.50
NISCH Q9Y2I1 1/20 0.50
CFTR P13569 1/20 0.45
GOPC Q9HD26 1/20 0.45
ADRA2A P08913 3/20 0.44
ADRA2B P18089 2/20 0.44
ADRA2C P18825 2/20 0.44
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
TAAR1 Q96RJ0 4/20 0.41
CSNK1A1 P48729 1/20 0.39
TYRO3 Q06418 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
F2RL1 P55085 1/20 0.37
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7579076 0.91 NISCH (0.52) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL3278270 0.82 MTOR (0.46) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL4729372 0.82 MTOR (0.48) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL2205006 0.80 F2RL1 (0.48) MTORADKNISCHADRA2AADRA2B
SCHEMBL698729 0.80 ADRA2A (0.60) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL8201456 0.80 MTOR (0.47) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL4363951 0.80 MTOR (0.47) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL10642682 0.80 F2RL1 (0.42) F2RL1
SCHEMBL28000044 0.80 ADRA2A (0.60) SLC6A2SLC6A4SLC6A3MTORADK
SCHEMBL8700070 0.80 MTOR (0.47) SLC6A2SLC6A4SLC6A3MTORADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116034089-A EMM-58 zeolite compositions, synthesis and uses 埃克森美孚技术与工程公司 2023-04-28 CN claimed
CN-114479795-A Expanded particle composite water shutoff agent, preparation method thereof and water shutoff construction method 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-110003869-B Crack plugging agent based on expanded particles and curable particles 西南石油大学 2021-04-06 CN claimed
US-20050261328-A1 Pharmaceutical composition comprising beta-3-adrenoceptor-agonists and antimuscarinic agents BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 US claimed
EP-1567149-A2 PHARMACEUTICAL COMPOSITION COMPRISING BETA-3-ADRENOCEPTOR AGONISTS AND ANTIMUSCARINIC AGENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-08-31 EP claimed
WO-2004047838-A2 PHARMACEUTICAL COMPOSITION COMPRISING BETA-3-ADRENOCEPTOR AGONISTS AND ANTIMUSCARINIC AGENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-06-10 WO claimed
EP-0003796-B1 SUBSTITUTED DIPHENYLMETHYL-IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM BAYER AG (DE) 1980-10-15 EP claimed
EP-0003796-A1 Substituted diphenylmethyl-imidazoles, their preparation and medicaments containing them BAYER AG (DE) 1979-09-05 EP claimed
JP-62205002-A None JP disclosed
JP-5078328-A None JP disclosed
CN-119731728-A Luminescent material, light emitting diode and display device 京东方科技集团股份有限公司 2025-03-28 CN disclosed
EP-3365819-B1 PHARMACOPHORES, COMPOUNDS AND METHODS HAVING APPLICATION IN THE TREATMENT OF CANCER THROUGH INHIBITION OF CYP17A1 AND CYP19A1 MANGOSUTHU UNIV OF TECHNOLOGY (ZA) 2023-06-07 EP disclosed
CN-116034089-A EMM-58 zeolite compositions, synthesis and uses 埃克森美孚技术与工程公司 2023-04-28 CN disclosed
CN-114479795-A Expanded particle composite water shutoff agent, preparation method thereof and water shutoff construction method 中国石油化工股份有限公司 2022-05-13 CN disclosed
EP-0003796-B1 SUBSTITUTED DIPHENYLMETHYL-IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM BAYER AG (DE) 1980-10-15 EP disclosed
US-4182624-A FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed
US-4182624-A FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed
EP-0003796-A1 Substituted diphenylmethyl-imidazoles, their preparation and medicaments containing them BAYER AG (DE) 1979-09-05 EP disclosed
EP-0003796-A1 Substituted diphenylmethyl-imidazoles, their preparation and medicaments containing them BAYER AG (DE) 1979-09-05 EP disclosed
EP-0003796-A1 Substituted diphenylmethyl-imidazoles, their preparation and medicaments containing them BAYER AG (DE) 1979-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261328-A1 Pharmaceutical composition comprising beta-3-adrenoceptor-agonists and antimuscarinic agents ADRB3, ADRB2, ADRB1 SLC6A2 381/4885SLC6A4 1183/4885SLC6A3 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.