Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949256 | 1.00 | CTSK (0.58) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL9970532 | 0.89 | ATM (0.54) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL12798890 | 0.88 | ATM (0.57) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL13489691 | 0.88 | ATM (0.57) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL416706 | 0.86 | CTSK (0.53) | CTSKPRTN3ATMTRPM8CTSL | |
| SCHEMBL15271790 | 0.86 | CTSK (0.53) | CTSKPRTN3ATMTRPM8CTSL | |
| SCHEMBL417361 | 0.86 | CTSK (0.53) | CTSKPRTN3ATMTRPM8CTSL | |
| SCHEMBL25465632 | 0.85 | TRPM8 (0.66) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL15238327 | 0.85 | ATM (0.57) | CTSKPRTN3ATMELANETRPM8 | |
| SCHEMBL2723524 | 0.85 | ATM (0.57) | CTSKPRTN3ATMELANETRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | XDH, XPA, TPX2 | CTSK 2560/4885PRTN3 785/4885ATM 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.