Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490230 | 0.92 | KMT2A (0.43) | PDE10AMEN1KMT2AMAPTHTR2A | |
| SCHEMBL13490201 | 0.91 | KMT2A (0.44) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490266 | 0.90 | PDE10A (0.41) | DHODHPDE10AMEN1KMT2ACYP11B1 | |
| SCHEMBL13490244 | 0.90 | DHODH (0.45) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490214 | 0.89 | SMN1; SMN2 (0.41) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490246 | 0.88 | TAS1R3 (0.40) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490213 | 0.87 | MAPT (0.43) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490281 | 0.87 | PDE10A (0.38) | DHODHPDE10AMEN1KMT2AMAPT | |
| SCHEMBL13490216 | 0.86 | RAB9A (0.40) | PDE10AMEN1KMT2AMAPTMAOB | |
| SCHEMBL13490204 | 0.86 | DHODH (0.41) | DHODHPDE10AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | DHODH 1426/4885PDE10A 1000/4885MEN1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.