Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3199563 | 0.99 | ALDH1A1 (0.51) | ALDH1A1HPGDGID4MEN1KMT2A | |
| SCHEMBL13490630 | 0.84 | SMYD3 (0.56) | GID4SMN1; SMN2NPC1RAB9AUSP30 | |
| SCHEMBL3222424 | 0.84 | NPC1 (0.60) | GID4SMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL13490474 | 0.83 | FPR1 (0.45) | GID4SMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3224400 | 0.83 | SMYD3 (0.55) | GID4SMN1; SMN2NPC1RAB9AUSP30 | |
| SCHEMBL13490398 | 0.82 | SMN1; SMN2 (0.45) | GID4SMN1; SMN2NPC1RAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL3222484 | 0.81 | SMN1; SMN2 (0.44) | GID4SMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL13490684 | 0.80 | EPHX2 (0.50) | GID4MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL13490676 | 0.80 | SMN1; SMN2 (0.53) | GID4KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14192814 | 0.80 | SMN1; SMN2 (0.53) | GID4KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | ALDH1A1 680/4885HPGD 4524/4885GID4 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.