Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.51 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3201873 | 0.99 | HTR2B (0.55) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL13490372 | 0.91 | MEN1 (0.54) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL13490618 | 0.91 | MEN1 (0.54) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL13490741 | 0.91 | MEN1 (0.54) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL14192268 | 0.91 | MEN1 (0.54) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| Hydrochloric Acid SCHEMBL3218463 | 0.90 | CXCR6 (0.53) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| Hydrochloric Acid SCHEMBL3213396 | 0.90 | CXCR6 (0.53) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL13490478 | 0.90 | CXCR6 (0.47) | HTR2BSMN1; SMN2MEN1NPC1PKM | |
| SCHEMBL3213194 | 0.87 | SMN1; SMN2 (0.62) | HTR2BSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL14192873 | 0.87 | SMN1; SMN2 (0.62) | HTR2BSMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | HTR2B 3456/4885SMN1; SMN2 746/4885MEN1 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.