Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3263803 | 0.94 | CXCR6 (0.43) | CXCR6MAPTPOLBHTR2BOPRK1 | |
| SCHEMBL13490400 | 0.90 | HTR2B (0.56) | CXCR6HTR2BSMN1; SMN2THRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL3201873 | 0.89 | HTR2B (0.55) | CXCR6HTR2BSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL13490618 | 0.83 | MEN1 (0.54) | CXCR6MAPTPOLBHTR2BSMN1; SMN2 | |
| SCHEMBL13490741 | 0.83 | MEN1 (0.54) | CXCR6MAPTPOLBHTR2BSMN1; SMN2 | |
| SCHEMBL14192268 | 0.83 | MEN1 (0.54) | CXCR6MAPTPOLBHTR2BSMN1; SMN2 | |
| SCHEMBL13490372 | 0.83 | MEN1 (0.54) | CXCR6MAPTPOLBHTR2BSMN1; SMN2 | |
| SCHEMBL3212293 | 0.83 | HCAR3 (0.45) | CXCR6HTR2BALDH1A1 | |
| SCHEMBL14192261 | 0.83 | HCAR3 (0.45) | CXCR6HTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL3218463 | 0.83 | CXCR6 (0.53) | CXCR6MAPTPOLBHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | CXCR6 3847/4885MAPT 2652/4885POLB 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.