Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085778 | 0.87 | MAPK1 (0.51) | MAPK1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL633629 | 0.83 | TDP1 (0.46) | VCAM1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4688384 | 0.82 | TDP1 (0.50) | MAPK1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL29154301 | 0.81 | TDP1 (0.45) | VCAM1MEN1KMT2ALMNAMAPT | |
| SCHEMBL28865817 | 0.81 | MAPK1 (0.49) | MAPK1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL8555024 | 0.81 | MAPK1 (0.51) | MAPK1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL28085781 | 0.79 | MAPK1 (0.50) | MAPK1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL30739792 | 0.79 | KMT2A (0.57) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL28295511 | 0.78 | MAPK1 (0.49) | MAPK1VCAM1MEN1KMT2ALMNA | |
| Acetic Acid SCHEMBL27660224 | 0.78 | TDP1 (0.50) | MAPK1VCAM1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | claimed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | claimed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | claimed |
| CN-107801378-A | PlX-8394 or P L X-7904 for the treatment of BRAF-V600 related diseases | 普莱希科公司 | 2018-03-13 | — | — | CN | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| CN-103517710-B | For the compound of kinases regulation | 普莱希科公司 | 2017-05-31 | — | — | CN | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215000-A1 | Production And Use Of Zinc Amides | SCLY, CBR3, SCO2 | MAPK1 3635/4885VCAM1 4340/4885MEN1 3970/4885 |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | GLRX3, SCLY, SFXN1 | MAPK1 3739/4885VCAM1 4086/4885MEN1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.