Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 11/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ATG7 | O95352 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497062 | 0.91 | ADK (0.41) | ADKXDHADORA2AATG7ALDH1A1 | |
| SCHEMBL16496534 | 0.90 | ADK (0.36) | ADKXDHADORA2AATG7ALDH1A1 | |
| SCHEMBL14081712 | 0.88 | ADK (0.35) | ADKXDHADORA2AATG7ALDH1A1 | |
| SCHEMBL4014575 | 0.88 | ADK (0.35) | ADKXDHADORA2AATG7ALDH1A1 | |
| SCHEMBL13494103 | 0.87 | ADK (0.34) | ADKXDHATG7PRKAB2PRKAG1 | |
| SCHEMBL4020234 | 0.85 | ABL1 (0.36) | ADKABL1EGFRSRC | |
| SCHEMBL13725076 | 0.84 | LMNA (0.33) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL4016824 | 0.84 | PRMT5 (0.45) | ADK | |
| SCHEMBL14081718 | 0.84 | PRMT5 (0.45) | ADK | |
| SCHEMBL16496977 | 0.84 | RET (0.36) | ADKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015637-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |