Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224949 | 1.00 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL10615093 | 0.90 | SMN1; SMN2 (0.81) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL1568754 | 0.89 | RAB9A (0.79) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL31530566 | 0.85 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2EPHX2GAA | |
| SCHEMBL31232828 | 0.85 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL30644009 | 0.85 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL8723879 | 0.85 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL8536908 | 0.85 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL11572813 | 0.84 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL28502280 | 0.82 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015211-A1 | SYNTHESIS OF OXAZOLINE COMPOUNDS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2010-02-11 | — | — | WO | disclosed |